Drug Encapsulation

Introduction

A range of applications including restaurants and hotels, waste and ecological, organic and inorganic, medical, pharmaceutical, electricity, engineering etc. are protected by immobilization innovation benefits and advantages (Dragostin et al., 2017).  It appears that this invention is of infinite value and potential and crosses any technical boundary. The technology of immobilization and its area of application is now so broad and complex in the pharmaceutical as a field of great concern, where real estate has changed to a great deal. Physical or chemicals modifications have been prepared for immobilization, but today more than one form of modification will apply the immobilization methods (Oliveira et al., 2017). For example, an improved entanglement with additional bonding strength is generated by a combination of entanglement and cross ties. Immobilization is a unique method itself, particularly through encapsulation, as encapsulation can also be linked (Akhtar et al., 2017).  This paper seeks to evaluate the significance of drug encapsulation within the medical fields.

Evaluate the Significance of Drug Encapsulation in the Medical Field

Drug encapsulation is a method of vesicular immobilization that surrounds or capsules the agents inside the framework vesicle of the sphere. As stated by Wang & Windbergs (2019), depending on its properties and preparation process, the biopolymer sphere structure may be built into a bilayer or one-layer sphere. Although the sphere immobilization systems of matrix form have no hollow cavity within its structure, the entire structure is instead solidified and filled with the biomaterial (Dragostin et al., 2017).  The Bilayer sphere is comprised of the hydrophilic polymer layer of the system, both outside and within. It is also used to hold hydrophilic or non-immobilization chemicals (Oliveira et al., 2017). The single sphere layer has only one hydrophilic biopolymer. The internal structure is exposed to another side of the hydrophobic biopolymer, which provides contact with the held agent. The agents are indefinitely stuck in the circle filled with biopolymer matrix, and also some matrix is diffusible to the agent (Gupta et al., 2016)

Drug procurement is the key step for deciding whether a medication has been effective or ineffective in pharmaceutical applications, regardless of how novel and effective the medication is if the product is incorrectly administered and if no medication is launched in the target area, the research and production of the drug will be significantly affected (Vahabi & Eatemadi, 2017). In addition, researchers should decide the most feasible and non-destructive delivery mechanism when developing a certain drug for a certain target. Therefore, effective drug distribution primarily depends on the drug manufacturer and its distribution path (Oliveira et al., 2017).

Key words: drug, encapsulation, immobilization, chemicals, agents,

References

Akhtar, A., Wang, S. X., Ghali, L., Bell, C., & Wen, X. (2017). Recent advances in arsenic trioxide encapsulated nanoparticles as drug delivery agents to solid cancers. Journal of biomedical research, 31(3), 177.

Dragostin, I., Dragostin, O., Pelin, A. M., Grigore, C., & Lăcrămioara Zamfir, C. (2017). The importance of polymers for encapsulation process and for enhanced cellular functions. Journal of Macromolecular Science, Part A, 54(7), 489-493.

Gupta, B., Poudel, B. K., Pathak, S., Tak, J. W., Lee, H. H., Jeong, J. H., … & Kim, J. O. (2016). Effects of formulation variables on the particle size and drug encapsulation of imatinib-loaded solid lipid nanoparticles. Aaps Pharmscitech, 17(3), 652-662.

Oliveira, M. S., Goulart, G. C. A., Ferreira, L. A. M., & Carneiro, G. (2017). Hydrophobic ion pairing as a strategy to improve drug encapsulation into lipid nanocarriers for the cancer treatment. Expert opinion on drug delivery, 14(8), 983-995.

Vahabi, S., & Eatemadi, A. (2017). Nanoliposome encapsulated anesthetics for local anesthesia application. Biomedicine & Pharmacotherapy, 86, 1-7.

Wang, J., & Windbergs, M. (2019). Controlled dual drug release by coaxial electrospun fibers–impact of the core fluid on drug encapsulation and release. International journal of pharmaceutics, 556, 363-371.